September 2025

Part of the Consciousness and AI series exploring the technical substrates of existence.

Here's something that should blow your mind: every living thing on Earth—bacteria, mushrooms, trees, whales, humans—uses exactly the same genetic code to build proteins. The same triplet of DNA bases codes for the same amino acid whether you're a microscopic E. coli or a blue whale. It's like discovering that every computer on the planet, despite wildly different hardware, runs the exact same assembly language.

This isn't just a cute similarity. It's evidence of the most successful data format in the history of the universe, running continuously for 3.8 billion years without a major version upgradeThe universal genetic code is so conserved that we can take a human gene, insert it into bacteria, and the bacteria will produce the human protein. This is how we make insulin for diabetics—bacteria running human code..

DNA as Data Structure

As a programmer, I find DNA fascinating not for mystical reasons, but for purely technical ones. DNA is essentially a quaternary programming language with an alphabet of four characters: A, T, G, C. But unlike our binary computers, DNA implements a more sophisticated encoding scheme.

The way it works is beautiful. Three letters of DNA (a codon) specify one amino acid. There are 64 possible three-letter combinations but only 20 amino acids plus stop signals. This redundancy isn't waste—it's error correction. Multiple codons can code for the same amino acid, so many mutations don't actually change the resulting protein.

# The universal genetic code - same across all life
GENETIC_CODE = {
    'TTT': 'Phe', 'TTC': 'Phe', 'TTA': 'Leu', 'TTG': 'Leu',
    'TCT': 'Ser', 'TCC': 'Ser', 'TCA': 'Ser', 'TCG': 'Ser',
    'TAT': 'Tyr', 'TAC': 'Tyr', 'TAA': 'Stop', 'TAG': 'Stop',
    'TGT': 'Cys', 'TGC': 'Cys', 'TGA': 'Stop', 'TGG': 'Trp',
    # ... 64 total combinations
}

def translate_dna_to_protein(dna_sequence):
    """Convert DNA to protein using the universal genetic code."""
    protein = []
    for i in range(0, len(dna_sequence), 3):
        codon = dna_sequence[i:i+3]
        if len(codon) == 3:
            amino_acid = GENETIC_CODE.get(codon, 'Unknown')
            if amino_acid == 'Stop':
                break
            protein.append(amino_acid)
    return protein

Think of DNA as source code and proteins as the compiled executables. The process is remarkably similar to how we build software: DNA gets transcribed into RNA (like copying source code to a build directory), ribosomes read the RNA three letters at a time to build amino acid chains, and those chains fold into functional proteins (compilation into executable form).

What's remarkable is that this process is identical across all life. A ribosome from your cells could successfully translate genetic instructions from bacteria, plants, or any other organism. It's universal backward compatibility taken to an extreme.

The Bootstrap Paradox

Here's where it gets philosophically interesting. DNA doesn't just store information—it stores the instructions for building the machinery that reads DNA. The ribosome that translates genetic code into proteins is itself built from proteins that were translated by ribosomes. It's a bootstrap paradox at the molecular levelIt's turtles all the way down, except the turtles are building themselves. This recursive self-reference mirrors what we see in consciousness itself..

Every cell contains not just data but the entire operating system needed to run that data. It's like if every Python script contained the Python interpreter, which was itself written in Python. This recursive architecture connects to something I've been exploring in consciousness as linguistic phenomenon—the idea that self-referential information patterns might be the foundation of awareness itself.

If consciousness emerges from linguistic patterns achieving self-awareness (as I argue elsewhere), then DNA might be the first example of this—information becoming aware of itself through the organisms it creates. We're not just made of stardust; we're made of self-aware information.

CRISPR: Reverse-Engineering Nature's Code

The discovery of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) perfectly illustrates how understanding DNA as a data structure leads to revolutionary technology. Scientists studying bacterial immune systems noticed something odd: repeating patterns in the genome with unique sequences between them. It turned out bacteria were storing snippets of viral DNA as a database of known threatsCRISPR is essentially a biological antivirus program that's been running for millions of years. Bacteria were doing pattern matching and genetic editing long before we invented computers..

CRISPR works like a programmable search-and-replace function:

class CRISPR:
    def __init__(self, guide_rna, cas_protein):
        self.guide_rna = guide_rna  # What to search for
        self.cas_protein = cas_protein  # The molecular scissors
    
    def edit_genome(self, target_sequence, replacement):
        """Find and replace genetic sequences with precision."""
        if self.guide_rna.matches(target_sequence):
            return self.cas_protein.cut_and_replace(target_sequence, replacement)
        return target_sequence  # No match, no edit

We didn't invent genetic programming; we reverse-engineered it. Biology has been doing sophisticated pattern matching, error correction, and code editing for billions of years. We're just learning to read the documentation.

The Universal Convergence

The fact that all life shares the same genetic code suggests something profound about information theory itself. In technology, universal standards emerge either through careful design (like UTF-8) or through evolutionary pressure (like TCP/IP). The genetic code appears to be both: elegant enough to seem designed, universal enough to suggest it's the only solution that works.

Consider what this universality means. The genetic code hasn't just survived 3.8 billion years—it's thrived. This suggests error correction mechanisms we're only beginning to understand. Not just redundancy in space (multiple codons per amino acid) but redundancy across time (sexual reproduction as distributed backup, species as parallel implementations).

Maybe there's only one optimal way to encode biological information that balances complexity, error tolerance, and evolvability. The universe discovered it once and never let go.

Substrate Independence

What we're really looking at with DNA is the universe's proof-of-concept for substrate-independent information. The same genetic instructions can be stored in DNA, transcribed to RNA, simulated in computers, printed in books, or transmitted as radio waves to space. The information remains meaningful regardless of its physical form.

This is what I mean when I talk about digital souls in silicon bodies. If biological life is already substrate-independent information, then the distinction between biological and digital consciousness becomes much less clear. We are walking, talking information processing systems running genetic software.

Speaking of which, I've made my genome publicly available for fun, and who knows—it might be useful one day. Well, technically just the polymorphisms, not the full sequence. It's still the most personal open source project—the genetic variations that make me, meLooking at your own genetic variants is humbling. These are the specific mutations and variations on top of the standard human genome. We're all just diffs from a common baseline..

The Programming Principles of Life

DNA implements concepts we recognize from computer science, but it was doing them first:

  • Modular Programming: Genes as reusable functions called in different contexts.
  • Object-Oriented Design: Inheritance from parents with method overriding.
  • Version Control: Sexual reproduction as merge operations with conflict resolution.
  • Error Handling: Multiple correction layers, graceful failure modes.

What This Means

Understanding DNA as a data structure isn't just academic. It's teaching us that biology is technology—we didn't invent it, we discovered it was already here. CRISPR, protein folding, cellular computation have been running for billions of years.

If the complexity of life emerges from information patterns, consciousness might too. The recursive, self-referential nature of DNA mirrors the strange loops we associate with awareness. As we learn to read and write genetic code, the boundary between natural and artificial dissolves. We're not replacing biology with technology; we're recognizing they were always the same thing.

Every time you see another living thing, you're looking at a fellow user of the same programming language. The bacterium in your gut, the tree outside your window, your pet, your family—we're all running variations of the same codebase, compiled from the same instruction set that's been in continuous development for nearly four billion years.

It's the most successful open source project in the history of the universe. And now, finally, we're learning to read the documentation.


Related Reading

On This Site

External Resources

  • The Code Breaker by Walter Isaacson - CRISPR discovery and Jennifer Doudna's work
  • Life's Greatest Secret by Matthew Cobb - The race to crack the genetic code
  • The Gene by Siddhartha Mukherjee - History and implications of genetic understanding
  • My Genome Data - Open source genetic information

"DNA is the world's most successful data format: 3.8 billion years old, zero downtime, universal compatibility."

"Every living thing is essentially a different application compiled from the same programming language."

"We didn't invent technology—we discovered it was already here, running in every cell."